Publications
Journal of Drugs In Dermatology – An Open-Label Trial of the Efficacy of 15% Aluminum Chloride in 2% Salicylic Acid Gel Base in the Treatment of Moderate-to-Severe Primary Axillary Hyperhidrosis
Katherine H. Flanagan MD and Dee Anna Glaser MD
Department of Dermatology, Saint Louis University School of Medicine, St. Louis, MO
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Primary focal hyperhidrosis (HH) is a chronic disorder of excessive sweating. A single-center, open-label study was performed to determine the efficacy and safety of 15% aluminum chloride (AC) in 2% salicylic acid gel base (SAGB) Hydrosal in adults with moderate-to-severe primary axillary HH. Thirty subjects were given 15% AC in 2% SAGB to apply to their bilateral axillae nightly for the first week, then twice weekly application as tolerated. The primary objective was change in mean Hyperhidrosis Disease Severity Score (HDSS) score from baseline to week 4.
Dermatology Times - Don't Sweat It - New Topical Formulation Effective for Hyperhidrosis
By Ilya Petrou, M.D. - Senior Staff Correspondent
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A newly formulated topical therapy appears to be significantly effective and well-tolerated in patients suffering from primary focal hyperhidrosis. The modified formulation offers a therapeutic option to patients who fail other topical therapies for their condition and/or where other treatment avenues are not an option.
St. Louis — Patients treated with a new topical formulation consisting of 15 percent aluminum chloride in a 2 percent salicylic acid gel base (Hydrosal, Valeo Pharma) demonstrate significant improvement from symptoms of axillary hyperhidrosis and report a high tolerability, according to the results of a recent study.
The 12-week, single-center, open- label study included 30 patients with moderate-to-severe primary axillary hyperhidrosis, who had a baseline score of 3 to 4 on the Hyperhidrosis Disease Severity Scale (HDSS).
Cutis - Hydrosal Professional
Valeo Pharma launches Hydrosal Professional in the United States. A specially formulated gel for individuals with hyperhidrosis or various degrees of excessive sweating, Hydrosal Professional is designed to reduce perspiration and odors.
full text...Skin and Allergy News - Topical Gel for Hyperhidrosis
Hydrosal Professional is available as a first-line treatment for excessive sweating. It is available only through a physician. The gel contains 15% aluminum chloride hexahydrate, which has proven to be more effective than other aluminum salts typically used in antiperspirants.
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